Treatment of Bowen's disease with topical dinitrochlorobenzene and 5-fluorouracil

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Topical Tretinoin and 5-Fluorouracil in treatment of epidermal nevus

Background: Epidermal nevus is a common skin hamartoma. Its definite treatment is difficult and in most cases the disease has recurrence. Objective: Evaluation of topical tretinoin 0.05% and 5 Fluorouracil (5FU) 5% in the treatment of epidermal nevus. Patients and Methods: Fifteen patients with epidermal nevus referred to skin clinic in Razi Hospital in Tehran whose diagnoses were confirm...

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The effect of topical 5- fluorouracil ointment along with epidermal abrasion in treatment of vitiligo

  Vitiligo is a common idiopathic acquired cutaneous pigmentary disorder resulting in depigmented skin. A wide variety of therapeutic modalities have been employed for its treatment, but none of them are satisfactory, in this study we have tested the effect of 5- fluorouracil 5FU on 54 patients with documented vitiligo in Kerman city. The following treatments were performed on three selected v...

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Successful Treatment of Vitiligo by Needling with Topical 5 Fluorouracil

Introduction: Vitiligo is a chronic acquired disorder presenting with depigmented macules and patches. The response to treatment is variable as no single therapy produces predictably good results. Needling with topical 5% 5 fluorouracil in vitiligo has been found to be promising, effective and safe modality of treatment. Materials and methods: Three patients with stable vitiligo were on medical...

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Treatment of conjunctival squamous cell carcinoma with topical 5-fluorouracil.

AIM To evaluate the efficacy of topical 5-fluorouracil (5-FU) alone, without concurrent surgery or radiotherapy, for the treatment of conjunctival squamous cell carcinoma. METHODS Eight patients affected by conjunctival squamous cell carcinoma (three recurrent cases, three incompletely excised, and two untreated cases) were treated with 1% 5-FU eye drops. Topical 1% 5-FU was administered four...

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Life-Threatening Reaction with Topical 5-Fluorouracil

A 67-year-old man developed a suspected adverse drug reaction during treatment with topical 5-fluorouracil (5-FU) for multiple actinic keratosis of the face, neck, and forearms. The man received topical 5-FU at a dosage of 0.5% for the actinic keratoses. After 1 week, he developed extreme lethargy, fatigue, fever, and mouth erosions. Several days later, and after discontinuation of 5-FU, painfu...

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ژورنال

عنوان ژورنال: Cancer

سال: 1976

ISSN: 0008-543X,1097-0142

DOI: 10.1002/1097-0142(197604)37:4<1633::aid-cncr2820370403>3.0.co;2-p